Project holder looking for a partner
Main topic(s) of interest : Graphene (Basic Research)
Brief description of project :
Polysaccharides and cyclodextrin derivatives: from synthesis to applications
We are experts in the field of biomaterial research with a focus on carbohydrate, bioorthogonal, and supramolecular chemistry. Currently, we focused on the modification of polysaccharides and cyclodextrins in a reproducible way and also the preparation and characterization of self-healable hydrogels using covalent and non-covalent click chemistry based on modified carbohydrates under physiological conditions.
First Name : Abolfazl
Last Name : Heydari
Country : Slovakia
E-mail address : abolfazl.heydari@savba.sk
Telephone : +421949133061
Project holder looking for a partner
Main topic(s) of interest : Graphene (Basic Research), Graphene (Applied Research and Innovation)
Brief description of project :
The project aims at development of next-generation intergrated biosensor technology based on layered (graphene etc) materials for viral screening and transcriptomics. Looking here for partners with expertise in molecular virology (pathogenesis, moprphogenesis, therapeutics) and molecular biology (ligand-aptamer interactions, SELEX, bioassay development).
Keywords : biosensor and bioelectronics, graphene field-effect transistor, diagnostics, immunology, long COVID
Expertise sought : molecular virology (pathogenesis, moprphogenesis, therapeutics) and molecular biology (ligand-aptamer interactions, SELEX, bioassay development)
First Name : Vivek
Last Name : Pachauri
Country : Germany
E-mail address : pachauri@iwe1.rwth-aachen.de
Project holder looking for a partner
Main topic(s) of interest : HBP (Basic and Applied Research)
Brief description of project :
Our FLAGERA-HBP consortium is urgently looking for a partner interested in doing computational modeling and/or data analysis of neurobiological mechanisms of Alzheimer's disease. As current partners are from France and the Netherlands, we are looking for potential partners from any of the other participating countries (Belgium, Bulgaria, Estonia, Israel, Lithuania, Romania, Slovakia, Slovenia, Turkiye or Taiwan). Please reach out as soon as possible to Jorge Mejias (j.f.mejias@uva.nl) if interested.
Keywords : Alzheimers disease, data analysis, computational modeling
Expertise sought : data analysis or computational modeling
First Name : Jorge
Last Name : Mejias
Country : Netherlands
E-mail address : j.f.mejias@uva.nl
Project holder looking for a partner
Main topic(s) of interest : Graphene (Basic Research), Graphene (Applied Research and Innovation)
Brief description of project :
Title: "Development of graphene-Hydrogel Composite Scaffold for Enhanced Cartilage Regeneration"
Objective: The objective of this study is to investigate the potential of a Mxene-hydrogel composite scaffold for cartilage regeneration, compared to traditional scaffolds.
Hypothesis: We hypothesize that the incorporation of graphene in hydrogel scaffold will enhance the mechanical properties and stimulate chondrogenic differentiation of stem cells, resulting in improved cartilage regeneration.
Methodology:
Preparation of graphene-hydrogel composite scaffold
Characterization of the composite scaffold and mechanical testing
Cell culture study using human mesenchymal stem cells (hMSCs) to evaluate cell proliferation, viability, and chondrogenic differentiation of hMSCs on the composite scaffold.
In vivo study in a rabbit model of cartilage defect to evaluate the efficacy of the composite scaffold in cartilage regeneration compared to traditional scaffolds.
Histological and immunohistochemical analysis of regenerated cartilage to evaluate the quality of regenerated cartilage tissue.
Expected outcomes: We expect that the graphene-hydrogel composite scaffold will demonstrate improved mechanical properties, enhanced chondrogenic differentiation of stem cells, and improved cartilage regeneration compared to traditional scaffolds.
Significance: The development of a Mxene-hydrogel composite scaffold has the potential to improve the clinical outcomes of cartilage regeneration, which is a major challenge in orthopedic medicine.
Keywords : Cartilage Regeneration, graphene-Hydrogel Composite
First Name : Mina
Last Name : Namwari
Country : Turkey
E-mail address : mina.namvari@sabanciuniv.edu
Telephone : +90 534 069 0232
